Zofran

For nausea and vomiting, relief can’t come fast enough. Ondansetron is a prescription medication used to prevent nausea and vomiting, but it takes time to make an appointment, go to the doctor and get a prescription. Skip the doctor’s visit and quickly consult with our licensed medical staff online. You’ll be on your way to feeling better in a fraction of the time.

Dosing Protocols

Please take 1 tablet by mouth as needed every 8 hours. 

FAQs

Does Zofran make you sleepy?

Drowsiness is a possible side effect of Zofran, but overall, it's rare to experience side effects with Zofran.

What is Ondansetron?

Ondansetron is the generic form of Zofran—it contains the same active medication as Zofran for a more affordable price.

When should I take Zofran?

If you're taking Zofran to prevent nausea caused by medication, you can take one Zofran tablet 30 minutes before your prescribed dose of medication, which allows for enough time for the Zofran to kick in and prevent those uncomfortable waves of nausea. Keep in mind that the maximum dose of Zofran is one pill, three times daily every 8 hours. Taking Zofran with antibiotics, for example, can help you reduce your side effects so you can finish your medication and prevent your infection from returning.

Does Zofran have side effects?

Side effects with Zofran are rare, but it is possible to experience mild side effects such as: constipation, headach, drowsiness, diarrhea. One important benefit is that Zofran can be taken with or without food! It can be hard to eat when you are feeling nauseous, so don’t feel pressure to eat before taking it. You will tolerate it just fine!

Who should not take Zofran?

While Zofran is generally well tolerated, and extremely helpful when experiencing nausea after starting a new medication, there are some drug interactions you’ll want to watch for. Zofran is a serotonin receptor blocker—if serotonin receptors are blocked, there will be more serotonin circulating around your body. An increase in circulating serotonin can be dangerous because there are other medications that allow for increased serotonin in your body—medications that help with anxiety, depression (SSRI’s), migraine medications (Triptans), and antibiotics like Linezolid. If you are on one of the mentioned medications while taking Zofran, you may be putting yourself at risk for Serotonin Syndrome, a condition that occurs when your serotonin levels are dangerously high. This syndrome can have mild symptoms such as experiencing shakiness, trouble sleeping, excessive sweating. More extreme symptoms are high fever, uncontrollable diarrhea, and uncontrollable shaking and body movements. Of note, if any of those side effects are to occur while taking Zofran, please stop taking the medication and seek medical attention immediately. Additionally, while cardiac side effects are definitely rare with Zofran, there are some reports of QT elongation when taking this medication, which is quite dangerous causing the heart to take longer to contract and relax. Who is at risk for this? Those who are taking antiarrhythmic medication, people with low potassium or magnesium levels, those who take antibiotics from the Fluroquinolone family (Ciprofloxacin, levaquin), or Macrolide family (Azithromycin). If you have a history of the below mentioned conditions, you should speak to your medical provider before taking Zofran: heart disease; history of irregular heartbeat; liver disease; low levels of magnesium or potassium in the blood; an unusual or allergic reaction to ondansetron, granisetron, other medications, foods, dyes, or preservatives; pregnant or trying to get pregnant; anxiety/depression and on SSRI’s; history of PK, breastfeeding.

Does Zofran work for motion sickness?

Zofran is not recommended for motion sickness. Ginger or Dramamine are still the best treatments for nausea caused by motion sickness, so be sure to include them alongside Zofran for complete protection from planes, trains, automobiles, and boats.

Can I take Zofran with alcohol?

Do not take this drug with alcohol, marijuana, or other recreational drugs. Wait until alcohol is out of your system before taking Zofran.

Important Safety Information

Keep all appointments with your doctor. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Risks

Accurate Information
Your BIOVERSE team will evaluate the health information you provide to make a treatment recommendation. If you do not provide full and accurate information about your current health and your health history it could lead to failure of a diagnosis or an incorrect diagnosis. This could impact your treatment recommendations. Please contact your provider with any health updates as they come up.

Treatment Failure
This medication is not 100% effective. There is a possibility it may only partially resolve the condition or not work for the condition at all. Should you find the treatment to not be working or you notice new or worsening symptoms or side effects we urge you to reach out to your provider. If there is an emergency situation, call 911 or seek immediate in-person medical attention.

Misdiagnosis or Delayed Diagnosis
As with an in-person doctor, there is a possibility for misdiagnosis or failure to diagnose a condition you may have. This can impact the treatment recommendation from your provider. Our BIOVERSE providers practice using evidence based guidelines to make informed clinical decisions.

Accepting or Declining Our Recommendation
Your healthcare is your decision. Our providers will provide thoughtful evidence based recommendations from the information you provide and the potential benefits and risks associated with the treatment. You should make an evaluation based on our information, relevant input from other providers in your care team and any other important information related to your health to make an informed decision. You are by no means required to follow our recommendation, but keep in mind there can also be risks associated with no treatment.

Alternative Treatment
The recommendation of your BIOVERSE provider is based upon your specific situation, however in some cases there may be alternative treatments available that could work for you. These alternative treatments may vary in how effective they are or require an in-person exam that we are unable to provide. Please message us with any questions or concerns you have regarding your treatment.